Daily diet of almonds is no magic solution for weight loss

Wednesday February 24 2016

Nut consumption has fallen over the last 20 years

Almonds contain a range of nutrients

"Desperate to lose weight?" asks the Mail Online. "Eat almonds! Handful a day 'wards off hunger and replaces empty calories from junk food'," it says, without any justification.

It's hard to see where the headline's over-excited promises of weight loss or reduced hunger come from. The study they write about showed an improvement in diet quality for a small number of people asked to eat almonds daily for three-weeks. However, it did not measure the effect of almonds on weight loss, dieting or hunger pangs.

The study, funded by the Almond Board of California, failed in its aims of showing improved bowel function, better bacteria in the gut, and signs of improved immune status. 

While the study did show improvements of seven to eight points on a healthy eating scale (range 1 to 100), this was based on questionnaires for just 28 adults and 28 children, during a short period of eating almonds. Healthy changes to diets need to last for years, not weeks, to make a difference to health.

Like other so-called superfoods, there is no evidence in this study to suggest that almonds have any particular powers of helping people to lose weight. However, they are a good source of fibre and nutrients.

The NHS Choices weight loss guide can help you lose weight in a sensible way through a combination of diet and exercise.

Where did the story come from?

The study was carried out by researchers from the University of Florida and was funded by the Almond Board of California, which has a clear interest in promoting the health benefits of almonds. 

The study was published in the peer-reviewed journal Nutrition Research on an open-access basis, so you can read it for free online.

The quality of reporting by the Mail Online and the Daily Express was below par.

In addition to the Mail Online's over-enthusiastic headline, the Daily Express suggested that eating almonds "could work wonders". Neither newspaper included any information about the study's failure to prove its hypothesis about immune function. The basic facts given in the stories were mainly correct, although uncritically and selectively reported.

The Mail claimed that people eating almonds "increased their protein and lowered their salt intake", although protein only increased on one measure (total protein foods) and not another (protein as a percentage of energy). Salt consumption was only lower for adults, with borderline statistical significance.

The obvious conflict of interest in terms of the study's funding was not reported.

What kind of research was this?

This was a randomised crossover study, where people were assigned to eat almonds or no almonds for three weeks, then switched to the opposite intervention after a wash-out period. The study was not blinded, meaning people knew when they were in the "almond" or "no almond" part, and there were no substitutes offered for almonds (such as another type of nut).

What did the research involve?

Researchers studied 28 parents and 28 children (one child per parent). They measured their bowel function (how many stools they passed in a week), any symptoms like constipation or bloating, the composition of bacteria in the gut (from stool samples), markers of immune function in blood and saliva tests, and overall diet quality (from questionnaires). The tests were repeated regularly during the study. 

People were asked to eat 1.5 ounces (42g) of almonds (adults) or 0.5 ounces (14g) of almonds (children) for one of two three-week study periods, and no almonds in the other three-week study period. Researchers then compared the test results for the periods when they did or didn't eat almonds, to see if there were any differences.

The researchers aimed to recruit 30 pairs of parents and children, but only managed 29, and one pair dropped out of the study early on. They had calculated that they'd only need 15 individuals to show a change in gut bacteria, but it is not clear whether 28 pairs was enough to reliably show a change in diet quality or bowel function.

Dietary quality was measured by questionnaires about food eaten in the past 24 hours, which people filled out several times throughout the study, including while eating almonds, while not eating almonds, at the start of the study and the end. Results were mapped against a healthy eating scale to give a score from 1 to 100, and comparisons drawn between the scores while eating almonds and not eating almonds.

What were the basic results?

Both adults and children had an overall average dietary score of 53.7 while not eating almonds, and a score of 61.4 when eating almonds. Looking at individual parts of the healthy eating index, while eating almonds they consumed on average more total protein foods, seafood and plants protein, and fatty acids. Adults ate fewer foods classed as being "empty calories". 

The researchers also reported "trends" for less empty calories for children and less salt for adults, but these differences were so small they could have been due to chance.

The researchers found no difference for any of their other planned measures – bowel function, gut symptoms, phyla of bacteria in stool samples, or immune markers. They say they found some difference in bacteria types, but not at the level they planned to measure. We don't know whether the small differences they found would have any effect on human health.

How did the researchers interpret the results?

The researchers said they had "rejected" their hypothesis that eating almonds would improve bowel function, because overall fibre levels did not rise and adults ate less fruit while eating almonds. They say their failure to find differences in gut bacteria or immune markers may be because the "dose" of almonds was too low.

However, they claim the study results, "confirm that incorporating almonds into a daily diet promotes improved diet quality".

Conclusion

Despite the excitement in the tabloid headlines, this is a very small study with not particularly surprising results. You would expect that adding a food with known nutritional value to a daily diet would increase the overall quality of that diet, for the time that people continued to eat the food in question. The researchers' more ambitious aims – to show that nuts improved immune system and bowel function – were not met.

In addition to its small size, the study had other limitations. As the people in the study were not blinded to the intervention period, this could have affected their answers to questionnaires. Also, the parents filled in the questionnaires for their children, which may have been appropriate, but has not previously been tested as an accurate method for these specific questionnaires. Most of the children were at child care or school, so the parent may not have known what they’d eaten during the day.

It is also reported that many children were less than enthusiastic about having to eat almonds, with complaints that they were "boring" and "dry and bland". Whether they would stick to the diet on a long-term basis is uncertain.

A major problem with this type of study is that changes to improve the quality of diet need to be long term if they are to have a significant effect on life-long health. Measuring the effects of adding one food to the diet for three weeks does not tell us anything about the potential effects of eating that food regularly for many years.

While this study may not have much to tell us about healthy eating, there are still plenty of good reasons to eat nuts, such as walnuts, brazil nuts, hazelnuts and almonds. Nuts and seeds contain healthy oils, protein and fibre. They make a good addition to a balanced diet, along with fresh vegetables, wholegrains, fruit, dairy products and fish. Choose unsalted nuts, so as not to eat too much salt.

Read more about the benefits of eating a balanced diet

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Air pollution 'kills 40,000 a year' in the UK, says report

Tuesday February 23 2016

The growing popularity of cars as a primary means of transport have contributed to the problem

Air pollution has been linked to a range of chronic diseases

What is the issue?

"Air pollution is contributing to about 40,000 early deaths a year in the UK," BBC News reports.

The figures are the conclusion of a report assessing the impact of air pollution on public health in the UK. The report, published by the Royal College of Physicians and the Royal College of Paediatrics and Child Health, discusses the lifelong impact of air pollution. It presents a number of recommendations to the public, businesses and governments to make changes and reduce air pollution.

The expert panel states: "Real change will only occur when everyone accepts this responsibility, and makes a concerted effort."

Who produced the report?

The report was produced by the Royal College of Physicians and the Royal College of Paediatrics and Child Health, and aimed to look at changes in the sources of air pollution over time, both indoors and outdoors. 

The report also looks to the future in assessing the impact of an ageing population and climate change, and the effect this has on society.

The two Royal Colleges formed a group of experts from medicine and environmental sciences to discuss current evidence, found through a search of the literature, and came up with some recommendations.

What does the report say?

The report suggests that every year in the UK, outdoor pollution is linked to around 40,000 deaths, and more with indoor pollutants.

Air pollution can have a damaging effect from when a baby is in the womb and continue throughout life to older age, playing a role in many chronic conditions such as cancer, asthma, heart disease, and neurological changes linked to dementia.

The expert panel feels the concentration limits set by the government and the World Health Organization are not safe for the whole population and leave certain groups vulnerable. The panel therefore provides a number of recommendations for action.

What did they look at?

The experts discussed:

  • changes occurring over the years in air pollution
  • composition of the air we breathe
  • effect of air pollution on early human development, including vital organs
  • effects of air pollution over a lifetime
  • identifying vulnerable groups
  • the cost of air pollution
  • how to change our future

What evidence did they find?

The report found there have been a number of factors, including legislation that has changed the composition and level of air pollution we are exposed to today. Air pollution is not a new problem in the UK, but over the years our perspective on the health risks has changed.

There had previously been a focus on pollution from solid fuel burning, such as coal – which, as a result, fell dramatically. However, this has been replaced by concerns about exposure to pollutants from transport sources, especially cars. Even the "cleanest" of engines can produce nitrogen oxides, ozone and particulates – small specks of matter, such as soot. All three may have a potentially harmful effect on health.

Evidence from the literature discussed the public health burden of air pollution and methods for better management for health improvements, cost savings and increases in quality of life.

Indoor sources of air pollution are not always considered; however, the report found a number of sources emitting a variety of substances, such as:

  • gas cookers
  • cleaning products
  • damp and mould
  • cigarette smoke
  • carbon monoxide

They concluded that indoor pollutants may cause several thousand deaths per year in the UK, and the experts felt this was an area to be studied further.

There was evidence that exposure to pollutants throughout life, from pregnancy to older age, can have lasting influences. However, the evidence of harm to unborn babies and the young child is not as strong as it is for adults.

The experts suggest this is because the topic is relatively new and has not been so heavily researched, or that the effects on the baby and child may be subtle and take longer to appear. In some cases, damage caused by exposure to pollutants in early childhood may not become apparent until adulthood.

Evidence was found to suggest that long-term exposure to air pollution is linked to:

The report also found evidence that poorer people tend to live in lower-quality environments and are more exposed to air pollution. This does not necessarily mean they are at increased risk, so long as concentrations do not exceed regulations.

What does the report recommend?

The report provides a number of recommendations for action and also further research. These are described below:

  • We are encouraged to act immediately to protect the health, wellbeing and economic sustainability for our generation and those of the future.
  • Governments are urged to work with local authorities and industry to make long-term changes.
  • Educate professionals and the public of the serious harms of air pollution.
  • Promote alternative transport to cars fuelled by petrol and diesel; this may be walking, cycling, and use of public transport or electric/hybrid cars.
  • Regulations to be put in place so that those causing the pollution are required to take responsibility for harming health. This should be at a local, national and EU level.
  • Effective monitoring of air pollution levels, ensuring that serious incidents are reported.
  • Local authorities to act in protecting public health where air pollution levels are high, this may involve road closures and other traffic control.
  • Regulators and local governments to ensure there is no inequality in exposure to pollutants between deprived and more affluent communities.
  • Protect groups that are at increased risk of health problems. This includes children, older adults, and people with chronic health problems.
  • Benchmarking for clean air and safe workplaces; that is seeking to set a gold standard for clean air and regularly checking that the standard is met.
  • Carrying out further research into the economic impact of air pollution and the benefits of tackling the issue.
  • Strengthen our understanding of the relationship between indoor air pollution and health, including the key risk factors.
  • Improve our understanding of how global social and economic trends are affecting air quality.
  • Improve air pollution monitoring through use of better technology.
  • Research into the effects of air pollution on health.

These recommendations are likely to cost the taxpayer money, but the report makes a compelling case that they will save money in the long term. 

The report's authors estimate that the adverse impact on public health caused by pollution costs the UK economy more than £20bn per year, which is just under 16% of the current annual NHS budget of around £116bn.

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Mobile phone use 'linked to poor sperm quality'

Monday February 22 2016

Radiation is known to damage sperm

Could checking your status sap your sperm?

"Men who talk on their mobile phones for an hour a day 'are twice as likely to have low sperm quality'," the Daily Mail reports.

Is the use of smartphones damaging men's sperm? The quick answer, based on the results of this study, is we don't know.

The men studied were already experiencing fertility problems, and had been referred to a fertility clinic for semen analysis. At the same time, they completed questionnaires on their mobile phone use.

The researchers found a couple of links between mobile phone use and sperm concentration. A greater number of men with abnormal concentration reported speaking on their phone for more than an hour a day, and speaking while their phone was on charge.

There were no links found for other measures of semen quality, and no significant link with where on the body the mobile phone was carried, such as the trouser pocket – despite media headlines to the contrary.

The study has several important limitations, however. This includes assessing the link between semen quality and mobile phone use, so it therefore can't prove cause and effect.

We don't know when the men's fertility problems may have started, or how well the phone use currently reported reflects longer-term use patterns. It is also a very small sample of men.

The researchers recommend carrying your phone in your shirt pocket and using an earpiece when making a call.

However, given that the study analysed both of these factors and found no link with sperm quality, we can't say whether this will have any effect on fertility. 

Where did the story come from?

The study was carried out by researchers from the Carmel Medical Center in Israel, and was published in the peer-reviewed medical journal Reproductive BioMedicine Online.

No funding sources have been reported and the researchers declare no conflict of interest.

The UK media has taken the opinions expressed in the study at face value without considering the research's limitations, which, to be fair to the researchers, were highlighted in the study itself.

There are also some factual inaccuracies in the reporting. The Daily Telegraph reported the "sperm levels of men who kept their phones in their pocket during the day were seriously affected in 47% of cases, compared to just 11% in the general population". This is incorrect.

The study actually reports that – of men who carried their phone within 50cm of their groin – 47% of them had an abnormal sperm concentration and 53% had normal concentration.

Of men who carried their phone more than 50cm away from their groin, just 11% had abnormal concentration, with 89% having a normal concentration.

The calculations using these numbers actually found no statistically significant link between the distance the phone was carried from the groin and sperm concentration.

None of the men in this study were from "the general population" – all had been referred to a fertility clinic.   

What kind of research was this?

This was a cross-sectional study of a sample of Israeli men referred for semen analysis, who also completed questionnaires on their mobile phone use.

As the researchers say, in around a third of infertility cases, the cause comes down to male-related factors.

Research has demonstrated an overall decline in semen quality over the past 100 years. The researchers suggest one contributing factor is radiofrequency electromagnetic radiation emitted from mobile phones.

A study like this has numerous limitations when it comes to providing evidence. These include the cross-sectional assessment method – which cannot prove cause and effect – the small sample size, and the fact all the men studied were already experiencing fertility problems.     

What did the research involve?

The study included 106 men who received semen analysis as part of their assessment for infertility at an IVF clinic in Israel in 2011 and 2012.

The men completed a questionnaire on sociodemographics, health and lifestyle. Heavy smokers, heavy drinkers and those with health issues thought to possibly affect their fertility, such as diabetes and vascular problems, were excluded. This led to the further exclusion of 26 men, leaving 80 for the final analysis, with an average age of 35 years old.

The men completed questions on their mobile phone use. They were asked about the number of devices used and how long they spent talking on it each day: less than 30 minutes, 30-60 minutes, 60-120 minutes, or more than 120 minutes a day.

They were also asked where they stored the device while talking (for example, the use of hands-free or earphones), carrying or charging. Overall, the researchers classed this as distance from the groin – greater or less than 50cm.

The researchers also asked how long the men had owned a mobile phone, whether they talked on the mobile while it was charging, and whether they talked in low-reception areas such as lifts and underground floors.

Semen quality – volume, sperm concentration, motility (how well they can "swim") and morphology (shape) – were assessed and analysed using standard World Health Organization definitions of normality and abnormality.    

What were the basic results?

The 80 men had owned a mobile for an average of 12.9 years. Most of the men had normal semen volume (86%), sperm morphology (99%) and motility (71%), and just over half had normal sperm concentration (57%).

Sperm concentration was the only measure that found significant links with mobile usage. Significantly more men with abnormal concentration spoke on the phone for more than an hour a day (61%) compared with those with normal concentration (39%).

Significantly more men with abnormal concentration reported speaking while their device was on charge (two-thirds versus one-third of those with normal concentration).

There was no significant link between sperm concentration and other factors, including the distance from the groin the mobile was carried, speaking in low-reception areas, or use of hands-free.

Aside from mobile use, there was a significant link between sperm concentration and smoking. Significantly more men with abnormal concentration had smoked (57% currently or in the past) compared with those with normal concentration (43%).

Data is not given for semen volume and sperm motility, but the researchers say there was no significant difference in mobile phone use between those with normal and abnormal measures.  

How did the researchers interpret the results?

The researchers concluded that, "Our findings suggest that certain aspects of cell phone usage may bear adverse effects on sperm concentration. Investigation using large-scale studies is thus needed." 

Conclusion

This cross-sectional study included just 80 Israeli men who were already experiencing fertility problems and had been referred for semen analysis. The men answered questions on their mobile phone use at the same time.

The research found a couple of links with sperm concentration – a greater number of men with abnormal concentration reported speaking on their phone for more than an hour a day, and speaking while their phone was on charge.

There were no links seen with semen volume and sperm motility. Sperm morphology couldn't be assessed because only one man had abnormal morphology.

The study has a number of important limitations, which means it can tell us very little about whether there could be a link between radiofrequency electromagnetic radiation and semen quality.

The study assessed semen quality and mobile phone use at the same time, and this can't prove cause and effect. Though the men could be said to be reporting on past use, we don't know when their fertility problems may have started – for example, how long they had abnormal concentration for – or how well the phone use reported reflects longer-term use patterns.

For example, if the men report speaking on their mobile phone for more than an hour every day or speaking while the phone was on charge, we don't know whether this is something they do occasionally or whether they have done this every single day for a number of years.

It was a very small sample of only 80 men, which means there are smaller numbers when splitting them into normal or abnormal factors of semen quality, and this increases the possibility that you find links by chance. You are likely to get more reliable links if looking at a sample of 800 or 8,000 men, for example.

This is also a specific population sample of Israeli men who may have different health, lifestyle and environmental influences from other populations, meaning you can't easily transfer the results.

Other limitations, which the researchers acknowledge, include the different types of devices used – which may emit different amounts of radiofrequency electromagnetic radiation – and the distance from mobile phone towers.

Ideally, you would need a cohort study that prospectively assesses the long-term mobile phone use of a large sample of young men who start off with healthy semen. There are, however, likely to be various logistical issues with such a study.

Evidence does suggest sperm quality has dropped over the past few decades. The now ubiquitous use of smartphones in developed countries, and the corresponding exposure to radiofrequency electromagnetic radiation, could be one factor.

Other suggestions include poor diet and exposure to artificial hormones like oestrogen. One well-established link – which the study did find – is smoking.

Overall, the question of whether mobile phone use and exposure to radiofrequency electromagnetic radiation could be having an adverse effect on male fertility is an important one, but it cannot be answered by this study. 

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Exercise in middle-age 'stops your brain shrinking'

Thursday February 11 2016

Improving blood flow through the brain may have a protective effect

Brain shrinkage has been linked with Alzheimer’s disease

"A new study has suggested that exercising in your 40s could stop the brain shrinking," The Daily Telegraph reports.

 A study found people with good fitness levels in their 40s had larger brains than their unfit peers when measured 20 years later. The concern is that people with smaller brains may be more likely to develop dementia.

The study, part of a big ongoing research project in the US (the landmark Framingham Heart Study) measured people's exercise capacity and heart and blood pressure reactions to exercise during a treadmill test, at an average age of 40.

The same people were assessed about 20 years later, with a repeat exercise test and an MRI scan to determine brain volume.

People with 20% less fitness compared to the average, had smaller brains by the equivalent of one additional year of ageing. A similar effect was seen for higher blood pressure or heart rate in response to exercise.

However, we don't know the importance of the brain size differences measured and as this was only done once, it is not clear whether the size had actually changed.

So we cannot be sure fitness levels directly caused the differences in brain size. But the research does add to the growing evidence that physical fitness and better mental capacity in older age go hand-in-hand. 

What is good for the heart tends to also be good for the brain. Read more about how exercise may reduce your dementia risk.

Where did the story come from?

The study was carried out by researchers from Boston University School of Medicine, Framingham Heart Study, Harvard Medical School, Broad Institute of MIT and Harvard and the University of California. It was funded by the National Institutes for Health and the American Heart Association. 

The study was published in the peer-reviewed journal Neurology.

Reports in the UK media overstated the certainty of the study. The Daily Mail's headline: "Being a couch potato shrinks the brain," makes the results sound more definite than they are. The report says that "failing to exercise" was the cause of smaller brains. 

The Daily Telegraph says the study "revealed … exercising when aged between 40 and 50 could help prevent the brain shrinking". However, the study did not look at whether people exercised, how much they exercised or at what age. It only included information about their fitness levels, blood pressure and heart rate.

What kind of research was this?

This is a prospective cohort study, which tracks people over a long period of time and compares information taken at different time points. It's a good way to look for links between factors – in this case between fitness and later brain size. However, it cannot prove that one thing causes another.

What did the research involve?

Researchers took a large group of people, average age 40, and tested their fitness levels using a treadmill. They recalled them 20 years later to repeat a fitness test and have an MRI brain scan and cognitive tests. They looked for links between fitness at the first test and brain size and cognitive skills 20 years later.

The fitness tests involved people exercising on a treadmill until they reached 85% of their maximum heart rate, calculated by age and sex. Fitter people are able to exercise for longer before reaching this level. This time was used to calculate people's total exercise capacity. People's heart rate and blood pressure were also monitored before and during the test.

The researchers excluded people from their first analysis if they already had cardiovascular disease, had been taking beta blockers (drugs that slow heart rate) or if they had dementia or any condition that could affect the brain scan or cognitive tests. They were also excluded if they were unable to complete the exercise test.

In their analyses, the researchers adjusted their figures to take account of the following confounders:

  • age
  • sex
  • the time between examinations
  • whether they smoked
  • whether they had diabetes
  • whether they had a gene linked to Alzheimer's disease
  • whether they took medicine to treat high blood pressure

What were the basic results?

People who had 20% lower fitness levels based on the exercise capacity test had smaller brain volumes when assessed in later life. Those with a higher heart rate and diastolic blood pressure while exercising also had smaller brain volumes. Higher systolic blood pressure was also linked to smaller brain volumes, but only when the researchers looked at the subset of people with high blood pressure.

There was no link between lower exercise capacity in mid-life and any measures of cognitive function (thinking ability) in later life.

How did the researchers interpret the results?

The researchers say their findings: "provide new evidence that lower cardiovascular fitness and elevated exercise blood pressure and heart rate responses in early to midlife are associated with smaller brain volumes nearly two decades later, thereby linking fitness over the life course to brain health in later life."

They say that encouraging people to be fit in middle age could improve healthy brain ageing, especially for people with raised blood pressure.

Conclusion

We already know that high blood pressure in mid-life is linked to increased chances of getting dementia in older age. Also, taking regular exercise in middle age has been linked to a lower chance of dementia.

This study adds to what we already know about links between having a healthy heart and circulation, and a healthy brain.

The study found that people who did well in fitness tests at around 40 years of age had fewer signs of brain shrinkage at around 60. However, this did not translate into signs that the brain was working less well – perhaps because people were not old enough to have shown signs of slowed cognitive function.

We don't know from the study whether fitness levels are directly linked to brain shrinkage in a causal fashion. Therefore we can't say whether any particular amount of exercise protects against brain shrinkage. However, the researchers suggest that better cardiovascular fitness provides better blood flow and oxygen delivery to the brain, helping to keep it healthy.

The study has some limitations; importantly, brain volume was only assessed once, at the end of life, so we don’t know how much people's total brain volume had changed over time. We don't know the likely effect of the differences in brain volume measured. Also, the researchers did not calculate the possible effects of carrying out many different calculations on one set of data, which can increase the likelihood of some findings being down to chance.

Exercise has so many benefits that it can be confidently recommended, despite any questions about this particular study. However, there is no 100% guarantee that healthy lifestyles, including exercise, can prevent dementia in later life.  

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New NICE guidelines on sun exposure warn 'tanning is unsafe'

Wednesday February 10 2016

Children need to take extra care from the sun

Just a single lunch break on a hot day can damage unprotected skin

"No safe way to suntan, new NICE guidance warns," BBC News reports. The guidelines, produced by the National Institute for Health and Care Excellence (NICE), also stresses the benefits of moderate sun exposure.

This will help prevent vitamin D deficiency; which is more common in the UK than many people realise. It is estimated that around one in five adults and older children (aged between 11 and 18) have low vitamin D status. The figure is around one in seven for younger children.

What are the risks of overexposure?

Sunlight contains ultraviolet A (UVA) and ultraviolet B (UVB) radiation, both of which can be harmful to the skin. (The guidelines do not discuss artificial sources of UV light, such as sunbeds, but these are also thought to be harmful).

Risks of overexposure to sunlight include:

Non-melanoma is a leading cause of disfigurement, with an estimated quarter of a million cases occurring each year in the UK. Melanoma is a leading cause of cancer deaths in younger adults. More than 2,000 people die every year in the UK from melanoma.

Overexposure can also cause premature ageing of the skin, which can lead to signs and symptoms, such as :

  • dryness
  • itching
  • wrinkling
  • enlarged blackheads
  • loss of skin elasticity

At-risk groups

Groups of people particularly vulnerable to overexposure include:

  • children (particularly babies) and young people
  • people who tend to burn rather than tan
  • people with lighter skin, fair or red hair, blue or green eyes, or who have lots of freckles
  • people with many moles
  • people who are immunosuppressed (that is, they have less resistance to skin problems as a result of a disease or use of particular drugs)
  • people with a personal or family history of skin cancer (even if their natural skin colour is darker than that of the family member who had cancer)
  • outdoor workers
  • those with outdoor hobbies, for example, sailing or golf
  • people who sunbathe
  • people who take holidays in sunny countries

Preventing overexposure

Avoid strong sunlight

Avoid spending long periods of time in strong sunlight. The sun is at its strongest from 11am to 3pm from March to October. It can also be very strong and have potentially damaging effects at other times. Even if it is cool or cloudy, it is possible to burn in the middle of the day in summer.

Wear suitable clothing

Skin should be protected from strong sunlight by covering up with suitable clothing, finding shade and applying sunscreen.

Suitable clothing includes:

  • a wide-brimmed hat that shades the face, neck and ears
  • a long-sleeved top
  • trousers or long skirts in close-weave fabrics that do not allow sunlight through
  • sunglasses with wraparound lenses or wide arms with the CE Mark and European Standard EN 1836:2005

Use sunscreen

When buying sunscreen, make sure it's suitable for your skin and blocks both ultraviolet A (UVA) and ultraviolet B (UVB) radiation.

The sunscreen label should have:

  • the letters "UVA" in a circle logo and at least 4-star UVA protection
  • at least SPF15 sunscreen to protect against UVB

Most people do not apply enough sunscreen. The amount of sunscreen needed for the body of an average adult to achieve the stated sun protection factor (SPF) is around 35ml or six to eight teaspoons of lotion.

If sunscreen is applied too thinly, the amount of protection it gives is reduced. If you're worried you might not be applying enough SPF15, you could use a stronger SPF30 sunscreen.

If you plan to be out in the sun long enough to risk burning, sunscreen needs to be applied twice:

  • 30 minutes before you go out
  • just before going out

Sunscreen should be applied to all exposed skin, including the face, neck and ears (and head if you have thinning or no hair), but a wide-brimmed hat is better.

Water-resistant sunscreen is needed if sweating or contact with water is likely.

Sunscreen needs to be reapplied liberally, frequently and according to the manufacturer's instructions. This includes applying straight after you've been in water (even if it is "water-resistant") and after towel drying, sweating or when it may have rubbed off.

Advice for babies and children

Take extra care to protect babies and children. Their skin is much more sensitive than adult skin, and repeated exposure to sunlight could lead to skin cancer developing in later life.

Children aged under six months should be kept out of direct strong sunlight.

From March to October in the UK, children should:

  • cover up with suitable clothing
  • spend time in the shade (particularly from 11am to 3pm)
  • wear at least SPF15 sunscreen

To ensure they get enough vitamin D, children aged under five are advised to take vitamin D supplements even if they do get out in the sun. Find out about vitamin D supplements for children.

Avoid tanning

There is no healthy way to tan. Any tan can increase your risk of developing skin cancer. Getting a tan does very little to protect your skin from the harmful effects of the sun. The idea that there is such a thing as a healthy tan is a myth.

The British Association of Dermatologists advises that people should not use sunbeds or sunlamps.

Sunbeds and lamps can be more dangerous than natural sunlight, because they use a concentrated source of ultraviolet (UV) radiation.

UV radiation can increase your risk of developing melanomas. Sunbeds and sunlamps can also cause premature skin ageing.

If you do want browner looking skin then fake tan is the way to go.

Sunlight and vitamin D

Vitamin D is essential for healthy bones, and we get most of ours from sunlight exposure.

We need vitamin D to help the body absorb calcium and phosphorus from our diet. These minerals are important for healthy bones and teeth.

A lack of vitamin D – known as vitamin D deficiency – can cause bones to become soft and weak, which can lead to bone deformities. In children, for example, a lack of vitamin D can lead to rickets. In adults, it can lead to osteomalacia, which causes bone pain and tenderness as well as muscle weakness.

Most people can make enough vitamin D from being out in the sun daily for short periods with their forearms, hands or lower legs uncovered and without sunscreen from March to October, especially from 11am to 3pm.

A short period of time in the sun means just a few minutes – about 10 to 15 minutes is enough for most lighter-skinned people – and is less than the time it takes you to start going red or burn. Exposing yourself for longer is unlikely to provide any additional benefits.

People with darker skin will need to spend longer in the sun to produce the same amount of vitamin D.

Groups of people who have little or no exposure to the sun for cultural reasons or because they are housebound or otherwise confined indoors for long periods, may be vitamin D deficient and may benefit from vitamin D supplements.

How long it takes for your skin to go red or burn varies from person to person. Cancer Research UK has a useful tool where you can find out your skin type, to see when you might be at risk of burning.

Vitamin D and pregnancy

Pregnant and breastfeeding women should take a vitamin D supplement to make sure their own needs for vitamin D are met, and their baby is born with enough stores of vitamin D for the first few months of its life.

You can get vitamin supplements containing vitamin D free of charge if you are pregnant or breastfeeding, or have a child under four years of age and qualify for the Healthy Start scheme.

Read more about vitamins and supplements in pregnancy

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Smoking bans linked to fewer heart attacks and strokes

Thursday February 4 2016

Smoking bans may benefit non-smokers' health most

The ban on smoking indoors in public places "has helped save the lives of passive smokers," says the Daily Mail.

The headline refers to a review of the effects of smoking bans in 21 countries, including England and Scotland. This found fewer admissions to hospitals for heart attacks and strokes following smoking bans. However, the bans didn't appear to encourage more people to stop smoking.

Some studies included in the review found a bigger reduction in heart attacks and strokes among non-smokers – who are no longer exposed to smoke in public places – than smokers, who are still exposed to their own smoke.

The difficulty with research into smoking bans is that you can't carry out the "gold standard" of research: a randomised controlled trial. Instead, we have to rely on observational evidence – for example, looking at trends in hospital admissions for heart attacks before and after a ban is introduced.

It's hard to prove that smoking bans have led to lower hospital admissions, rather than other things, such as putting tobacco prices up. But this research suggests they have, particularly for non-smokers.

Where did the story come from?

The study was carried out by researchers from the Cochrane Tobacco Addiction Group, which is part of the Cochrane Collaboration of international healthcare researchers. It was funded by the Health Research Board Ireland and University College Dublin. The study was published in the peer-reviewed Cochrane Database of Systematic Reviews on an open-access basis, so it is free to read online.

The Sun, Mail Online and The Daily Telegraph focused on results from the smoking ban in England, which was introduced in 2007. While they were reported accurately, these results were published in the British Medical Journal (BMJ) in 2013, so are not particularly new. The Guardian gave a good overview of the research, including links to the original studies.

What kind of research was this?

This was a systematic review of all the studies previously published on the effects of smoking bans on health. Systematic reviews are the best way to get a balanced picture of all the evidence on a topic. However, they are only as good as the studies they include.

In this case, there were no randomised controlled trials, so the researchers had to rely on observational studies of varying quality.

What did the research involve?

This research was an update of a previous systematic review of the evidence around smoking bans, published in 2010. Since then, more countries have introduced smoking bans and more studies have been published.

Researchers searched databases of published research, looking for all relevant studies that met their criteria. They then examined all the studies to record their methodology, results and assess the study for risk of bias.

Usually, Cochrane reviews carry out a meta-analysis, where they pool the data to give overall results from all the studies. Because of the different types of research they found, they were unable to do this for this review. Instead, they grouped together studies looking at the same health outcomes, then summarised the results for each group.

What were the basic results?

Researchers found 77 studies and looked at the effects of a smoking ban on:

  • cardiovascular health (mainly heart attacks and strokes)
  • respiratory health (mainly asthma and chronic obstructive pulmonary disease, or COPD)
  • the health of newborn babies
  • numbers of deaths from smoking-related diseases
  • numbers of people who smoked, plus quit rates and tobacco consumption

They found "persuasive" evidence from 33 out of 43 studies that fewer people were admitted to hospitals with heart attacks and unstable angina, and evidence from five out of six studies that fewer people were admitted with stroke. Some studies found that non-smokers benefited from a bigger reduction in the incidence of heart attack and stroke.

The review also found national rates of smoking-related diseases (including heart disease) went down after smoking bans were introduced, and continued to fall. Eight out of 11 studies showed a reduction in deaths from smoking-related diseases.

The picture was mixed for respiratory health, with conflicting results from the 21 studies reviewed; some found a reduction in COPD or asthma admissions, but others did not.

The researchers found pregnant women were less likely to smoke after bans had been introduced, and some studies found fewer babies were born prematurely or with low birth weight. However, they say the quality of the evidence was too low and the study results were too conflicting to be sure.

The evidence was also unclear about the effect smoking bans had on how much people smoked, and how many smoked. While some studies showed a dip in smoking and an increase in attempts to quit just before and shortly after a smoking ban was introduced, these reductions didn't last.

As most countries were already showing a trend away from smoking, it's difficult to determine whether the bans played a part. Other factors, such as the price of tobacco and economic outlook in a country, might have affected the results.

How did the researchers interpret the results?

The researchers said the results gave "more robust support" for their previous conclusions that smoking bans were linked to better health outcomes. "There is moderate quality evidence that countries and their populations benefit from enacting national legislative smoking bans with improved health outcomes from reduced exposures to passive smoke, specifically cardiovascular disease," they said.

However, they added that the evidence for fewer deaths from smoking-related diseases was "low quality".

Conclusion

There is no doubt that tobacco smoking harms health and causes a great deal of disease and death. The World Health Organization (WHO) estimates that tobacco is responsible for one in 10 adult deaths worldwide.

The question is whether smoking bans can help reduce the harm caused by tobacco. This summary of research suggests they can, particularly for people who are non-smokers. While it's hard to get good-quality evidence about the effects of smoking bans, comparisons of data from hospitals and national registries before and after a ban is helpful.

However, we can't be sure the effects being measured are solely down to the smoking ban. For example, bans on trans fats in foods in some countries could also have contributed to a drop in heart attacks and stroke. However, it's useful to have information from lots of different countries, all showing similar trends over time.

The evidence around the numbers of people who stop smoking after a smoking ban is disappointing, but the researchers point out that smoking bans are only one way to encourage people to quit.

If the effects of a smoking ban are simply to protect people who don't smoke from the harmful effects of tobacco, that is still a big improvement.

Read more information and support about how to give up smoking

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Just one hour of sitting down may increase diabetes risk by a fifth

Wednesday February 3 2016

Lack of exercise may disrupt the normal workings of the body’s metabolism

Many of us are living increasingly sedentary lifestyles

"Every extra hour sitting down can raise your risk of type 2 diabetes by a fifth," the Daily Mirror reports. The paper reports on a study that used an accelerometer – a device that tracks movement – to look at the effects of sedentary behaviour on type 2 diabetes risk.

Researchers in the Netherlands measured the time that almost 2,500 middle-aged or older people spent sitting or lying down in one week, using an accelerometer. They found that people who had type 2 diabetes spent on average 26 minutes longer sitting or lying down, compared to people without diabetes.

From this, the researchers calculated that each additional hour of being sedentary increased the chances of a person having diabetes by 22%. It made little difference whether people sat for long periods or got up for regular breaks – the important thing was the overall amount of time spent sedentary.

Importantly, the study doesn’t tell us if people’s sedentary behaviour led to them getting diabetes, or whether people became more sedentary after getting diabetes. However, it provides more evidence that spending a lot of time physically inactive is likely to be bad for our health.

It is currently thought that the most effective ways you can reduce your type 2 diabetes risk include eating a healthy dietlosing weight (if you're overweight) and becoming more physically active.

Where did the story come from?

The study was carried out by researchers from Maastricht University and was funded by the European Regional Development Fund, numerous institutions from the Netherlands and by grants from three manufacturers of diabetes medication. The study was published in the peer-reviewed journal Diabetologia on an open-access basis, so it’s free to read online.

Most of the UK media’s reporting was accurate, although not all the reports made it clear the study does not prove that being sedentary causes diabetes. The Daily Telegraph did make this clear, while the Daily Mail said researchers had ruled out the possibility that diabetes made people more sedentary, which is not strictly true.

The Sun described sedentary people as "couch potatoes" who were "lazing around" – ignoring the fact that people who work at computers or drive for a living sit for much of the day.

What kind of research was this?

This is a cross-sectional observational study. Researchers wanted to see if people’s activity levels were linked to whether they had type 2 diabetes, or risk factors for type 2 diabetes. Cross-sectional studies can give useful information suggesting a link between two factors – in this case, activity levels and diabetes. However, as snap-shots of information, they can’t tell us whether one causes the other, because we don’t know which factor happened first.

What did the research involve?

Researchers measured the activity levels of 2,497 people aged 40 to 75, 29% of whom had diabetes, using accelerometers. The devices were worn for eight consecutive days and measured whether they were sitting, standing or lying down, as well as speed of movement.

The researchers tested people’s glucose tolerance (a measure for diabetes) and other health measures, such as cholesterol, blood pressure and weight. After adjusting the figures to take account of known diabetes risks, they looked to see whether people’s time spent sitting or lying down was linked to their risk of having diabetes.

As well as whether people actually had diabetes, the researchers considered whether they had impaired glucose tolerance (a restricted ability to process glucose, which is often a precursor of type 2 diabetes) or metabolic syndrome. This is a collection of warning signs for diabetes, including impaired glucose tolerance, a high waist measurement, high levels of unhealthy fats in the blood and high blood pressure.

With the activity data, researchers looked at overall time spent sedentary (other than night-time sleeping), at how many "sedentary breaks" people had – for example, times when they got up and walked around or stood – and for what duration they remained sedentary at any one time.

They adjusted their figures to take account of the following confounders:

  • age
  • sex
  • education level
  • whether they smoked
  • how much alcohol they drank
  • whether they had walking difficulties
  • their health
  • body mass index (BMI)
  • how much higher-intensity exercise they took

Finally, they calculated the risk of having diabetes or metabolic syndrome for each additional hour spent sedentary.

What were the basic results?

People with normal glucose tolerance spent on average 9.28 hours a day sedentary, compared to 9.38 hours for people with impaired glucose tolerance and 9.71 hours for people with diabetes.This means that people with diabetes spent on average 26 minutes longer each day being sedentary.

This equated, said the researchers, to a 22% increased risk of getting diabetes for each additional hour of time spent sedentary (odds ratio [OR] 1.22, 95% confidence interval [CI] 1.13 to 1.32). The chances of having metabolic syndrome was 39% higher (OR 1.39, 95% CI 1.27 to 1.53).

The numbers of sedentary breaks, and duration of sedentary episodes, made little difference once the researchers had adjusted their figures for confounding factors.

How did the researchers interpret the results?

The researchers said this was the first time anyone had shown a link between sedentary behaviour measured by objective accelerometers, and diabetes risk, in a big group of adults. They say their results have "important implications" for public health, and that "consideration should be given to including strategies to reduce the amount of sedentary time in diabetes prevention programmes".

The researchers said their analyses of the data looking specifically at people with more severe diabetes  those taking insulin  suggest that the severity of illness is not linked to the likelihood of being sedentary, so it is more likely that inactivity causes diabetes.

Conclusion

This study adds to existing evidence which suggests the amount of time we spend physically inactive, either sitting or lying down, could have a poor effect on our health. It does not, however, prove that sitting for long periods causes diabetes.

The study has some strengths, including its size and the fact that activity levels were measured objectively. Activity levels in the Netherlands are likely to be similar to those in the UK, so these findings may also apply to us. However, the cross-sectional design of the study means it cannot show that sedentary behaviour is a cause of diabetes, even when taking account of the researchers’ assertion that their analysis of people with more severe diabetes makes this more likely.

Although the researchers adjusted their figures to take account of many confounding factors, they did not look at some other lifestyle aspects that could be important in developing diabetes, such as what people ate and family history of diabetes.

Study results aside, we already know that exercise and physical activity are good for cardiovascular health, so it’s not surprising that spending much of your day sitting down is likely to be a bad thing.

It can be hard to keep active if you have a job that requires you to spend a lot of time sitting down, such as being a taxi driver or working on a computer. This study gives one more potential reason to make sure you spend as much time as possible being physically active, whether that’s going to the gym, taking a walk, using the stairs instead of the lift, or just dancing around the kitchen while making dinner.

Read more about how you can incorporate a fitness regime into your day-to-day activities

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